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DOI: 10.18544/PEDM-22.04.0067
Pediatr Endocrino Diabetes Metab 2016;22,4:175-180

The coexistence of two independent disease units – Graves’ disease and growth hormone deficiency in a 13 year old female patient

Maria Klatka, Katarzyna Kozyra, Agnieszka Pola, Izabela Rysz

Key words 

hyperthyroidism (Graves’disease), somatotropin hypopituitarism, development period

Abstract

Introduction. Graves’ disease (MGB) is the most common cause of hyperthyroidism in children and adolescents. This condition is more common in girls than boys, in a ratio of about 5:1. The coexistence of Graves’ disease (MGB) with growth hormone deficiency (GHD) is not common. Much more often GHD connects with hypothyroidism. Case report. We present the case of 13-year old female patient with Graves’ disease, diagnosed at 10 years of age and growth hormone deficiency, which was confirmed at the age of 12. Currently, the girl was qualified to growth hormone therapy. Conclusions. 1) Described by our case is interesting because of the rarity of coexistence Graves’ disease with growth hormone deficiency. 2) GH deficiency often accompanies hypothyroidism. Note, however, that hyperthyroidism may be associated with short stature in the course of growth hormone deficiency. 3) The coexistence of endocrine disorders in childhood is not uncommon, so the diagnosis of one disease entity should not exclude further observation for the presence of other endocrine disorders.


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DOI: 10.18544/PEDM-22.04.0067
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